Blanc氯甲基化反应

Blanc Chloromethylation Reaction

　在缩合剂ZnCl₂或H₂SO₄、CH₃COOH、AlCl₃、SnCl₄等存在下，芳烃与甲醛和浓盐酸作用，可以向芳环上导入氯甲基：

反应机理

   以苯的氯甲基化反应过程为例:

反应实例

参考文献

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[8]  F. Klages, Einfuhrung in die organische Chemie, p 62 (Berlin, 1961)